Maybe.
I think people sometimes put too much emphasis on the drawing ability of well-known actors/actresses. It's definitely a factor especially with independent films and in the past, certain actors like Will Smith/Tom Hanks seem to pull people in. I still think the marketing campaign, the premise, and if it's a popular franchise beforehand are just as important factors if not more nowadays.
Brad Pitt, for example, is usually considered an A-List star, but World War Z is the biggest opening weekend in his career and it finished second at about $66 million. I think marketing, zombies general appeal, and World War Z name factored into its success. Probably more than Brad Pitt's presence.